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Fat loss & metabolicField ref.
MOTS-c Metabolic Support Protocol
Insulin sensitivity and exercise-adjacent metabolic support
Overview
MOTS-c is a mitochondrial-derived peptide most associated in the community with metabolic health and exercise performance rather than direct appetite suppression (unlike the GLP-1 class). Protocols are typically dosed around training days.
Dosing schedule
Informational only — not medical advice.
| Phase | Amount | Frequency | Timing | Route |
|---|---|---|---|---|
| Standard | 5–10 mg | 2x/week | Pre-training | subcutaneous injection |
Administration
Reconstitute with bacteriostatic water. Commonly dosed on training days rather than a fixed daily schedule.
Cycle length
8 weeks on, 4 weeks off.
Precautions
- Human data is limited relative to its animal-model literature — treat metabolic claims as preliminary.
- Monitor blood glucose if you are diabetic or pre-diabetic and using other glucose-affecting compounds concurrently.