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Semax Nasal Cognitive Protocol
Focus and cognitive-performance support
Overview
Semax is a synthetic ACTH-fragment peptide administered intranasally, most often used by the community on an as-needed basis for focus/cognitive tasks rather than as a continuous daily regimen — many users cycle days on and off based on need.
Dosing schedule
Informational only — not medical advice.
| Phase | Amount | Frequency | Timing | Route |
|---|---|---|---|---|
| Standard | 2–3 sprays (approx. 0.5–1 mg) | 1x/day, as needed | AM | nasal |
Administration
Administered as a nasal spray from a reconstituted solution; store the reconstituted spray refrigerated between uses.
Cycle length
2 weeks on, 1 weeks off. Many users report a subjective "plateau" with continuous daily use and prefer cycling on/off.
Stacking
- Selank — Frequently combined — Semax for focus, Selank for calm; community convention treats them as complementary rather than redundant.
Precautions
- Can cause mild jitteriness/overstimulation in sensitive individuals, especially at higher doses.
- Limited long-term human safety data outside its origin (post-stroke) research population.